INTRODUCTION Dengue and chikungunya are both arboviral diseases caused by single-stranded RNA viruses ( DENV). They are both vigorous viruses spread by the Aedes mosquito. Both the diseases are occurs at temperature and ecoregions on spared all over the world. Dengue fever was first explained as “ Water intoxication” correlated with flying insects in a Chinese medical encyclopedia in 992 Since the Jin Dynasty (265-420 AD). The word “dengue” is derived from the Swahili phrase Ka-dinga pepo, meaning “cramp-like seizure”. The first clinically recognized dengue epidemics transpired practically in Asia, Dengue virus has 4 distinct serotypes (DEN-1, DEN-2, DEN-3, DEN-4). Infection with one serotype gives lifelong immunity against a particular serotype and less immunity against other serotypes. Flavivirus includes yellow fever, West Nile, Japanese encephalitis, and tick-borne encephalitis viruses. Dengue viruses belong to the genus Flavivirus in the family Flaviviridae....